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Lomibuvir

Glpbio
Catalog No:GC61002-10mM (in 1mL DMSO) CAS No.:1026785-55-6 MDLNo:C25H35NO4S Brand:Glpbio purity: 特性: Purpose:Lomibuvir(VX-222)是一种选择性的非核苷聚合酶抑制剂,靶向丙型肝炎病毒NS5B聚合酶(RdRp)的拇指口袋2,Kd为17nM。Lomibuvir抑制1b/Con1型HCV亚基因组复制子,EC50为5.2nM。Lomibuvir优先抑制延长的RNA合成,而非从头合成的RNA。DMSO: ≥ 32 mg/mL (71.81 mM)
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